Details, Fiction and megatomi.com
Details, Fiction and megatomi.com
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Our new Distinct+ tissue clearing approach is the one method that delipidates samples without improve in morphology and with minimal impact on structural integrity.
Megatome can be a vibrating microtome meant to portion a broad selection of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With large blade vibrating frequency and minimized blade deflection, Megatome allows substantial-throughput tissue sectioning with uniform floor profile, and negligible tissue damage and information loss.
Antibodies could get weeks to diffuse by means of just a few millimeters of tissue, using a steep labeling gradient from surface area to core.
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SE employs a rotational electrical area to disperse extremely electromobile molecules (such as antibodies or surfactant micelles) all over a porous sample devoid of detrimental electrically charged structures within the tissue. This permits two-4 day clearing of intact organs,
Our preformulated EasyIndex Remedy raises and homogenize the refractive index of delipidated tissue samples, rendering them totally clear. This allows mild penetration into the sample and makes sure the acquisition of significant-resolution, in-emphasis picture data.
Megatome can be a novel microtome that permits for top-precision sectioning of an array of tissue samples – from organoids, to arrays of animal organs, to intact human brain hemispheres – with small tissue harm and knowledge reduction.
eFLASH is a swift tissue labeling method which allows for uniform total-organ staining in twenty rounds of labeling.
The SmartSPIM light-weight sheet microscope gives unparalleled resolution and acquisition velocity during intact tissue volumes, though its modular design and style allows you to update and customize specific components.
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Both down load a release or produce a distribution zip as outlined over. Unzip the archive to the sought after place.
Leverage the Obvious+ tissue clearing process, along with eFLASH and patented stochastic electrotransport technologies, to speedily crystal clear and label full organs. Key highlights and functions incorporate:
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